The intention of this investigation is to know how it affects the labor exclusion to persons in situation of physical disability in its life project. This study was realized in the city of Santiago de Cali, Colombia; taking like population, five persons, in ages between 38 and 50 years, of both sexes. It is a question of a study explorativo of qualitative order, in which the information was gathered across the application of a semistructured interview, also three tests were projective. Thanks to the obtained results it was possible to admit that the aspects of the project of life that more turned out to be affected were the projections to future and the self-fulfillment, weigh that he contributed to the labor exclusion, it was possible to identify that these aspects turned out to be modified by the same disability condition and that the effect of the exclusion ended up by being a resultant fortifier to reach the projections and raised plans.