Periodontitis is an infectious disease that is characterized by a set of alterations that progressively affect the supporting tissues of the teeth, due to the presence of inflammatory gingival lesions, the formation of periodontal pockets with destruction of the connective tissue insertion to the root and alveolar bone loss. Its etiology for many years has been attributed to the presence of periodontopathic bacteria; However, studies carried out in recent years demonstrate that the presence of some members of the Herpesviridae family in the periodontium and the presence of pathogenic bacteria could favor the onset and progression of periodontal diseases. This review aims to present the published evidence that allows the presence of some viral herpes to be related to the development of periodontitis and its main role in the etiology.