One of the most important viruses in felines worldwide is the Felv (Feline Leukemia) since it has great impact on the cats where it depresses its immune system by making it more susceptible to acquiring another type of diseases, in addition to this delays growth and sometimes it can cause death; Vaccination prevents disease or persistent infection. Objective Describe the historical-epidemiological characteristics of the Feline Leukemia Virus (FELV), in Colombia addressing descriptive aspects of the disease. Sources of Information Four recognized data sources were used (Proquest, Science Direct, Sage Journals, Google Academic) in the same way the Mendeley bibliographic reference manager. Selection of studies Initially, 4,127 items and bibliographic reviews were found, of which 3.154 were eliminated by being duplicated, leaving 973 studies, after this a third selection was made 302 articles and to finalize, 53 items that cover the topics of interest were chosen. Exclusion criteria Articles that do not have a focus related to the research topic were excluded, which are in languages other than English, Spanish or Portuguese, items that are focused on other species or articles that do not have full access to information. Results REVISION DE LITERATURA 13 According to the cases reported from feline leukemia in different areas of the country, the FELV has a high prevalence in Colombia, since this disease is one of the main retroviral diseases that affects felines of all ages; On the other hand, there are few cases in our country where evidence of the epidemiological impact is reported, however, this is one of the main reasons for veterinary consultation. Conclusion Feline leukemia is one of the retroviruses that causes more involvement in felines that after its appearance can cause a large number of diseases and occasionally death; For this virus there is no specific treatment or medication that completely cure the animal, however, the most effective prevention method is vaccination as it avoids persistent infection.