ECMO therapy was developed by John Gibbon in 1950 as a means of oxygenating blood through a membrane oxygenator during prolonged operations on extracorporeal circulation. In recent years, the use of ECMO therapy is increasingly recommended in Intensive Care Units, making it possible to provide cardiac and respiratory support in patients with cardiac and pulmonary problems; however, the need to improve the educational processes for patients in therapy and their families has become evident due to the complexity of the therapy and its possible complications. Objective. Promote the understanding of ECMO therapy in relatives of patients undergoing such therapy through the design of a multimedia guide. Qualitative study of a phenomenological type with a semi-structured interview technique in which 4 ecmologist nurses participated; the pre and post interviews were recorded and transcribed. A web page was designed for family caregivers of patients on ECMO therapy. Results. After executing the multimedia guide, the informants reported that the relatives of patients on ECMO therapy decreased their level of anxiety and worry; they were more autonomous to make decisions, their doubts were cleared and the workload of the ecmologist nurses of said health institution decreased. Conclusions. Providing educational tools aimed at relatives of patients on ECMO therapy decreases the level of anxiety, gives them more participation in the recovery of patients. The use of ICT facilitates understanding and participation, being easily accessible with clear and detailed information on what they needed to know.