The Ministry of National Education and the national government have established teaching guidelines that favor the entrepreneurial potential of students. In the case of the I.E. Barrio San Nicolás in the city of Medellín, some actions have been taken in favor of its teaching, among them, recognizing the importance of entrepreneurship within the curriculum and isolated topics have been included in the curriculum of the area of technology and computer science, but this has not been enough, it is necessary, in addition to the above actions, a micro curriculum that guides teachers for their teaching, defining the skills that students need in the formation of an entrepreneurial mindset. Therefore, the need arises to rethink the actions implemented so far, in order to strengthen the teaching and acquisition of entrepreneurial skills in sixth grade students of the I.E. The first step then is to build and apply an instrument that seeks to identify aspects related to entrepreneurship and its teaching, adapted to teachers and students. The results of the instruments show the need to propose a transversal pedagogical project in entrepreneurship, mediated by a Virtual Learning Environment (VLE) and designed according to the ADDIE methodology (Analyze, Design, Develop, Implement, Evaluate) until the development phase, which will aim to contribute to the achievement of entrepreneurship competencies in sixth grade students of the I. E Barrio San Nicolás de Medellín, through the inclusion of pedagogical and methodological tools, ludic and didactic material and learning resources, through digital tools that will facilitate the achievement of the mentioned competences.