Salmonella spp is an important bacterium in swine production and epidemiology in general, this microorganism is considered an important causal agent of zoonosis, generating high risks for public health because it is difficult to identify, since some individuals are asymptomatic carriers, becoming amplifying reservoirs. In epidemiology it is relevant, since outbreaks due to this bacillus have been reported in different countries, resulting in high morbidity and mortality rates in populations, as a consequence of strains resistant to antimicrobials, denoting a responsibility towards producers, who sometimes make a bad prophylactic use and implement antibiotics as growth promoters in swine productions. The purpose of this review is the study and analysis of scientific literature, which shows the current incidence of Salmonella in swine production and its role in the presentation of foodborne diseases (FBD), as well as prevention and control measures to minimize the risk to public health, including the use of growth promoters in swine feeding and the implications of their use in the prevalence of the microorganism and microbial resistance. Consequently, the review made it possible to compile relevant information on Salmonella, to evaluate its trajectory and evolution, the influence of therapeutic malpractice on the generation of bacterial resistance and to conclude that Salmonella is a highly pathogenic microorganism, easily transmissible and a focus of importance in epidemiology, public and animal health.