The present analysis of literary documentary review will address issues related to obesity and depression in the adolescent population, with the object of study being to deepen the investigative contributions in a systematic way at the Latin American level, as a methodology the qualitative approach was implemented, the method used is based on in the consultation of secondary sources of search engines and scientific and official pages specialized in the clinical area, published in Latin America between the years 2010 and 2022. This study had a sample of 60 related scientific articles, which were organized under a bibliographic matrix. To conclude, it is essential to note that both depression and obesity represent a problem for the population of the Latin American territory, due to the fact that currently there are unhealthy practices on their part, among which are mainly little physical activity and poor food, with a consumption of junk food without having foods that are beneficial for health. The foregoing is worrying, since these customs are essential throughout life due to the benefits that they bring to both physical and mental health of people, improving the quality of life