Introduction: It is known the relationship between dynapenia and sarcopenia that results in an additional increase in the risk of morbidity and mortality in the general population and with a progressive increase according to age, from the age of 30 thanks to the decrease in muscle mass and strength, affecting exercise capacity, quality of life and mood. Objective: To determine the prevalence of dynapenia and sarcopenia in patients in cardiac rehabilitation of a Colombian hospital, with measurements of strength and biochemical markers. Methods: Cross-sectional study. Patients over 40 in cardiac rehabilitation at least once a week. The force measurement was performed with a hand dynamometer, the muscle mass was measured using a bipolar impedancemeter, the measurement of gait speed with the 6-meter walk test. Measurements of growth hormone (GH), free testosterone, somatomedin IGF-1 and cortisol were taken. Results: The decrease in muscle strength was more prevalent in men (n = 15, 19.4%) than in women (n = 5, 10%). The prevalence of dynapenia was 15.7% and sarcopenia 0%. The GH results were 0.27 (0.08-1.18), testosterone 5.9 (0.3-8.5), IGF-1 126 (95.5-169), cortisol 13.9 (11.2-18.4). The most frequent pathologies of the patients in the program were myocardial infarction; angioplasty and stent implantation. Conclusions: The prevalence of dynapenia was 15.7%. No difference was found between the biochemical markers in patients with and without dynapenia.