The proposed research project aims to characterize, through an evaluation model, the performance of students of Industrial Technology of the Technological Faculty of the Francisco José de Caldas District University, in knowledge related to nanoscience and nanotechnology, in the process of teaching learning, Through the mediation of communicative elements such as moodle platform and its different resources, videos, forums, chat, questionnaires and games. Initially the students' knowledge in basic knowledge about nanoscience and nanotechnology is evaluated, according to conditions such as age, gender, current semester, number of credits and experience in virtual courses, with these data the characterization using the techniques of descriptive statistics , Finally after interacting in the platform and receiving advice, is again evaluated in order to contrast those results.