This monograph focuses on the bibliographic analysis of chloride treatment systems in wastewater, in order to identify the most effective and viable systems for the elimination of these compounds and to improve water quality, in compliance with environmental and public health standards. To achieve this general objective, three specific objectives were proposed: to describe the types of chloride removal treatment, to identify the parameters that influence the efficiency of the treatment systems, and to establish which is the most adequate system for the removal of chlorides in wastewater. The methodology used consisted of a bibliographic review of scientific and technical articles published from 2010 to the present, using search engines specialized in the subject. The results obtained made it possible to describe the different chloride treatment systems, their characteristics and efficiency, identify the parameters that influence their performance and compare the different systems to establish which is the most appropriate according to the application context. It is concluded that there are several chloride treatment systems that can be effective in the elimination of these compounds in wastewater, but the choice of the most appropriate system will depend on the specific conditions of each situation, so during the development of this work these different systems are grouped into physical, chemical, biological, and special treatments, in order to present their main characteristics, efficiency, and other important factors for their development.