Population ageing brings with it an increase in pathologies such as cognitive impairment and dementia, which affect activities of daily living and quality of life. Objective: To estimate the level of quality of life and correlate it with sociodemographic and clinical variables in patients with mild cognitive impairment in the metropolitan area of Bucaramanga. Methodology: This is a cross-sectional study focused on analyzing the level of quality of life of adults with mild cognitive impairment, with a sample of 40 adults, all with a score in the Mini-Cog test <=2 points, from the metropolitan area of Bucaramanga and the PURE cohort. To assess quality of life, a visual analog scale of 0 to 10 points was applied, Spearman's correlations between quality of life and continuous clinical variables. Results: The 40 older people had a median age of 77.3 years and were mostly women (82.5%), 22.5% had alterations in the clock subtest and 27.5% in the memory subtest. The current quality of life was estimated at a median of 8/10 points, showing relationships between current quality of life and previous quality of life at 0.4125* and current quality of life with later quality at 0.489*. In the current quality of life, the number of inhabitants in the household is correlated with 0.6620*. Conclusion. 82.5% of the sample were women between 75 and 85 years old. Primary education prevailed, with 62.5% as the highest level of education; Only 2.5% have college degrees. High levels of HDL cholesterol are associated with a better perception of quality of life.