SMEs represent a relevant sector in the Colombian economy; however, their lack of competitiveness has reduced their level of success. One of the factors that have been detected in the face of these competitiveness problems has been the lack of technology that supports their business processes and leverages decision making, this largely originated by the limited budgets they have and the perception of needing large investments when acquiring information systems. This paper explored and compared the traditional infrastructure, Cloud Computing and Grid Computing, based on the factors that should be considered to conduct a study of the total cost of ownership to determine which options may be viable for Bogota's SMEs in the textile sector. Likewise, six interviews were made to SMEs of the textile sector in Bogota to contrast the information systems, their investment in technology, type of infrastructure and the way they manage technology-related costs in such a way that they could be compared against the factors investigated in the literature. According to the research carried out, the differentials that were found in terms of expense attributes between On premise infrastructure, Grid and Cloud Computing, are mostly part of investment expenses where the attributes that must be taken into account for the infrastructure are more numerous. On premise and the Grid compared to Cloud Computing, due to these investment expenses, SMEs tend to direct their decisions towards Cloud technology.