BACKGROUND. Meningiomas are the single most common brain tumor. The incidence of these tumors increases with age; different studies have shown that meningiomas usually appear after the age of 50. These tumors are more common in women than in men, who are twice as likely to suffer from the condition. Surgery is the primary form of treatment, which can be curative with complete resection. If the tumor is unresectable or other treatments such as surgery and radiotherapy have failed, hormonal therapy or chemotherapy may be considered. There is limited information about the clinical, demographic, and histopathological characteristics of these tumors in the population of Bogotá, Colombia. OBJECTIVE: To evaluate the expression of progesterone receptors in patients over 18 years old who have been diagnosed with meningiomas in a high-complexity hospital in Bogota, Colombia, and to describe the demographic and histopathological characteristics of these patients. METHODS: This is a descriptive and retrospective case series. Patients with meningioma who underwent surgical resection at a high-complexity hospital in Bogota, Colombia, from 2016 to 2019 were retrospectively identified and studied. Demographic variables, such as age and gender, were extracted from the clinical chart. Indirect immunoperoxidase staining was carried out for PR (progesterone receptor) and Ki67. PR is analyzed as positive and negative, and Ki67 proliferation index was determined. RESULTS: 32 meningiomas from patients who underwent surgery were available for analysis. 25 (78.1%) were positive to PR. 71.8% were females, and 93% were World Health Organization (WHO) grade I. Meningothelial (28%), fibrous (25%), and transitional (25%) were the most frequent subtypes, correspondingly. Ki67 mean value was 1.14 (0.11-10.71). CONCLUSION: Our case series showed a greater frequency of meningiomas in women, with a high progesterone receptor expression and a low Ki67 proliferation rate. This data correlates with literature worldwide.