He purpose of this research is to determine the factors that influence the increase in competitiveness and the optimization of the productive processes within the distribution centers, which are indispensable for the organizations at the time of remaining and staying in force before the demands of the current globalized market. The main contribution of this work is to provide guidelines and directions to increase competitiveness and optimization in the logistics and the business sector of the city, hoping that the application of these might generate a positive impact on the innovative ecosystem of the district of Santa Marta. The technique used to obtain the data was centered on a documentary compilation of academic databases, as well as a bibliographic review and documentary analysis of secondary and governmental sources that investigate competitive factors and process optimization in companies, with the aim of generating discussion and analysis in this regard from the perspective of both the authors and professional experts in the area of knowledge.