This paper presents the mechanical response of pile groups in a representative average geotechnical profile of the clayey soils of the Bogotá savannahs. The structure-soil interaction analyzes were performed using 3D finite element method in the Midas GTS NX software, a computer resource recently acquired by the Research Group on Disaster Attention and Prevention, Risks and Resilience (GIDPAD), within which this work was carried out. For the numerical simulations of the pile groups, the following parameters were used: group configurations, pile spacings, pile diameters and pile lengths. The stratigraphic profile used for the simulations was determined using information from field and laboratory tests from more than one hundred geotechnical studies, including in-situ tests such as the standard penetration test (SPT) and the piezocone (CPTU), carried out for the First Line of the Bogotá Metro and for other public and private investment projects, from which a database of geomechanical parameters for the clayey soils of the city's lake deposit was consolidated. In the analyses, the pile groups were subjected to gravity loads, lateral loads and, in some cases, to a combination of both. Between the load states and the study parameters, 567 combinations were generated. The results of this work are, on the one hand, the efficiency of pile groups under gravity loads, deformations and bending moments in piles obtained from finite element method analysis. Then, results of influence of the parameters on the results of efficiency, deformations and stresses of pile groups are presented.