This degree work is part of an investigation of exploratory-descriptive, which has the objective to propose a methodology for the integration of Environmental Management Systems, Safety and Health at Work and the Globally Harmonized System applicable to the Coordination of inventories and tools Refinery Management Barrancabermeja ECOPETROL SA Initially, the common requirements in ISO 14001, OHSAS 18001 and the Globally Harmonized System and applicable to the supply process dangerous chemicals are determined, then the diagnosis of the current state of the process is presented against the requirements identified in the above standards . Finally the integration methodology, risks affecting the environment and human health associated with the process are identified, the actions necessary to comply with current standards are defined and a mechanism that allows early mitigate these risks is presented, strengthening practice behavior assurance area operators to raise awareness of these risks to which they are exposed and how to prevent them.