This research aims to make the first approach of management in terms of biology and the possible consideration of organizations as living and complex systems. To that end, we review the development of the administration throughout its history and then we deal with life from multiple perspectives primarily molecular biological level, classic and evolutionary biology. We did a review of well-known authors on these issues of life and complexity as Francisco Varela, Humberto Maturana, Ricard Solé, Brian Goodwin, Lynn Margulis, Kauffman, Darwin, Ilya Prigogine, Duncan Watts, and more, to try to approach a more clear understanding from different disciplines, mainly biology. Once understandings have been made on biological and complex phenomena, we made a comparison with organizations and see if they can be considered biotic systems in accordance with the characteristics they possess and their similarity in processes, elements and interrelationships from biology.