Many authors view schizophrenia as a neurodevelopmental disorder. Knowledge of whether patients have morphologic variants that occur during the development of different anatomic areas of the brain and an understanding of the relation between such variants and brain development or prenatal exposure to possible noxae could provide clues about the events that lead to schizophrenia. Nonspecific morphologic variants that occur during the first and second trimesters of gestation, which are known as minor physical anomalies (MPA) and