We would like to raise several concerns regarding the article “Effects of preparation method, shear force, and exposure to collagen on release of growth factors from equine platelet-rich plasma” by Textor et al. 1 In their study, the authors tested the hypothesis that preparation method, exposure to shear force, and exposure to collagen would affect the release of growth factors from equine platelet-rich plasma. However, some important conclusions derived from their results may not have sufficient statistical power, and readers might be at