The economic analysis of technological options is a complement to biophysical research. The objective of this work was to estimate the economic advantages of incorporating new varieties of cotton, to reduce the production costs of cotton in the Sinú Valley, department of Córdoba, and to make the crop more competitive; since the surface harvested in Colombia in 2015 decreased by 39%, due to the high production costs of more than 5 million per hectare and low yields of 680 kilos of cotton fiber per hectare with losses of $1,157,827