654 Objectives To evaluate the added value of SPECT/CT in melanoma patients, examining whether SPECT/CT showed additional sentinel nodes (SN) in comparison with planar images, provided better localization of the sentinel nodes and if this additional information influenced surgical approach or patients' management. Methods 262 patients (female 145; male 117; mean age 53.9; range 18-90 y) with melanoma (T1-T3N0M0) were included in this prospective eleven-center study. They underwent dynamic and static SN scintigraphy