Background Sjögren9s syndrome (SS) is a common, autoimmune exocrinopathy characterized by symptoms of dry eyes and mouth present in 0.7% of the European American population. Gene expression profiling (GEP) has previously demonstrated overexpression of transcripts induced by interferons (IFN) in SS patients. Objectives In this study, we sought to identify and characterize underlying genetic contributions to dysregulation of IFN pathways in SS. Methods IFN signature genes of interest were selected
