Background: Biliary complications (BC) still constitute the “Achilles heel” of pediatric liver transplantation (LTx). The aim of this study was to describe the incidence of BC and analyze the impact of surgical treatment of BC on longterm patient and graft survival. Patients and Methods: We retrospectively reviewed 429 primary LTx performed between 01/07/1993 and 01/12/2010 (226 post-mortem and 203 living donors). The median recipient age was 1.6 years (range: 0.2-17.5). The main indications for LTx were biliary atresia (58%) and