Reports of Drosophilidae visiting palm and other spiked inflorescences are scattered in the literature, but this is the first systematic treatment of such flower visitors from the neotropics. Drosophilids in two new genera and four new species were found aggregating at inflorescences of palms in Ecuador and Colombia: Palmophila ecuadoriensis Grimaldi, n. gen., n. sp. on Wettinia maynensis; and Palmomyia incerta Grimaldi, n. gen., n. sp. on Geonoma undata, Chamaedorea linearis, and Phytelephas seemannii. Palmophila rozeni
