Background: We have recently observed a number of patients from Colombia with a distinctive endoscopic lesion characterized by multiple gastric hemorrhagic lesions, predominantly in the fundus, in the absence of known predisposing conditions, such as physiological stress, portal hypertension, or chemical injury (alcohol, NSAIDS), which are usually associated with acute hemorrhagic gastritis. Objectives: 1) to define the correlation between the endoscopic appearance and the histopathological characteristics of the gastric