HOUGHTON-TRIVINO, Natalia et al. Comparison of the transcriptional profiles of patients with dengue fever and dengue hemorrhagic fever reveals differences in the immune response and clues in immunopathogenesis. Biomédica [online]. 2010, vol. 30, n. 4, pp. 587-597. ISSN 0120-4157. Introduction. Dengue infection demonstrates a wide spectrum of clinical manifestations from mild disease (dengue fever) to severe dengue hemorrhagic fever, but the immunopathogenic mechanisms involved in disease severity are not clear