Detailed information of geographic distribution is critical for the conservation and management of endangered and endemic taxa. Such knowledge is limited for the Santander Poison Frog (Andinobates virolinensis), a threatened frog endemic to the Cordillera Oriental of the Colombian Andes. Here, we use new and historical data to model the potential distribution of this species and estimate its extent of occurrence. Our model predicted that suitable habitat exists on the western slope of the Cordillera Oriental in Santander, Boyacá