in a nuclear medicine laboratory where are performed computed tomography exams, a free gestural interaction interface contact is an ideal solution and highly interactive for preview images and three-dimensional models in a safe, quick and clean way, this allows a natural and intuitive navigation on the data obtained to analyze qualitatively clinical findings and to dinamize traditional visualization methods. Objectives: to evaluate the use by doctors and patients of gestural interaction interfaces in clinical environments where use images and 3D models of diagnosis. Methods: using open source libraries for the design of natural interfaces, we have implemented a system based on the tracking and recognition of hands and fingers using the Kinect sensor, which allows anyone intuitively navigate, only with gestures, through captured images and captured three-dimensional models by a tomographic image acquisition system, processed by InVesalius Software, which is an open-access software that provides high-quality 3D reconstruction of medical images. Results: images and three-dimensional models acquired by brain gammagraphy equipment SPECT (Single Photon Emission Computed Tomography) were used to test the usability of the interactive system. After a brief explanation about the system¿s functionality, 5 patients with psychiatric or neurological symptoms was allowed to navigate through of their own images and reconstructed models getting a significant improvement in the level of understanding of the technique and results by the patient. Laboratory medical staff was also instructed in the use of the system, creating a rapid and dynamic access point to the diagnostic images and models obtained. Conclusion: gestural interaction interfaces that use devices like the Kinect are an inexpensive tool and high accuracy that provide the possibility of a quick and clean navigation with images and 3D reconstructions achieved through SPECT using the software InVesalius. The developed interface can be used to manage various types of software that use images and 3D models by directed gestural control of the mouse and its events (click, click sharp, right click, scroll up, scroll down, etc.). Implementing software that allows adding automatically records obtained in real-time to interactive system is in progress.