Motorcycle use for urban trips in Latin America has grown significantly in recent years. The researchers used qualitative methods to understand the motivations of motorcycle mode users that might contribute to this growth in six cities: Barranquilla, Bogota (Colombia), Sao Paulo, Recife (Brazil), Caracas (Venezuela), and Buenos Aires (Argentina). Researchers used semi-structured interviews and focus groups to gather data from six categories of motorcycle users: motorcycle taxi drivers, motorcycle taxi users, motorcyclists for goods delivery in urban areas, motorcyclists for private use, owners in the process of selling their motorcycles, and potential motorcyclists (those seeking to buy motorcycles). Common themes emerged across the six cities, including the time advantage that motorcycles offered versus public transportation and congested auto traffic, the reasonable cost of motorcycles versus other transport modes, the culture of motorcycle use, and the vulnerability of motorcyclists to traffic injury and death. In the analysis of the data, the authors identify the main factors for motorcycle adoption and use, compare the results to existing literature, and outline emerging issues for future research.