Attention deficit and / or hyperactivity disorder is a syndrome that presents alterations from the psychological, behavioral and neuromotor point of view. It was an analytical empirical study, with predominantly quantitative information and with a descriptive and inferential scope. Its main objective was to identify the relationship between the clinical subtypes of ADHD, the neuromuscular soft neurological signs and the cognitive evoked potentials. 58 children with this diagnosis between 6 and 10 years of age in Colombia were evaluated from the clinical and neurophysiological perspective. Associations were made between neuromuscular soft neurological signs (SNB), cognitive evoked potentials (PEC) with visual and auditory modality in children aged 6 to 10 years, enrolled in school who presented clinical subtypes of ADHD with a predominance of inattentive, hyperactive or combined. The detection of SNBs was carried out by adapting an evaluation protocol called Risk Factors, academic history and soft neurological signs in children with ADHD. The PECs were evaluated through the analysis of the amplitude and latency of the waves N100, N200, P300, to determine the response time of mental processing, using a software called Sierra WaveTM version 6.0.33. Results: Results were obtained: 77.6% were boys and 31.4% were girls, 74.1% corresponded to the combined subtype, 24.1 inattentive and 1.7% corresponded to the hyperactive subtype. The most frequent SNBs were: alteration in graphestesia, alteration in left-right identification, alteration in eye tracking, alteration in coordination in sequential digital opposition, postural alteration and Synkinesia. Children with ADHD and their respective subtype and compared to PECs, there was evidence of a trend towards a different modality for each subtype. In the subtype combined, a prolonged latency and a decrease in amplitude were observed in auditory modality and the same tendency for the inattentive subtype in visual modality, an association between gender and subtypes was found with a pValue <0.005 (0.005) with a low degree of association . Likewise, an association was found for the auditory modality N100 wave in the combined subtype. Conclusions: Children diagnosed with ADHD with a combined clinical subtype presented a higher percentage than the others, not being the same for the hyperactive subtype. In the combined subtype, the male gender predominated and in the inattentive one an equal frequency was observed for the female and male gender. The inattentive subtype presented up to 6 SNB contrary to the combined subtype that presented up to 10 neurological signs, being more predominant in the inattentive subtype the signs of eye tracking, synkinesis, graphesthesia and for the combined subtype the signs of graphesthesia, in the left-right identification , in eye tracking, in sequential digital opposition coordination, postural alteration and synkinesis. In the auditory modality cognitive evoked potentials, a trend was found in the prolongation of latency in the N100, N200 and p300 components and a lower wave amplitude in the three channels. 7 Significant differences were found in the N100 wave in the three auditory modality channels, the latency being higher according to the mean for the combined subtype. It is recommended to deepen the knowledge of ADHD and especially, direct it towards investigations of the disorder in the female gender since there are few studies that frame the different characteristics in this genre. Also, it is suggested to standardize the soft neurological signs detection test in children with and without ADHD to extrapolate to the general population, and furthermore, it is necessary to continue with the study by expanding the size and age range of the sample so that the findings from the evaluation of SNB and neurophysiological characteristics from the PEC. It is important to say that this project was part of a macroproject called Assisted Diagnostic System for the Identification of ADHD on the registry of Cognitive Evoked Potentials, which was carried out at the Autonomous University of Manizales in conjunction with the University of Manizales, the National University of Colombia and Colciencias.