The objective of this systematic review is to evaluate the scientific evidence on educational innovation in optometry published nationally and internationally between the years 2008 and 2018. The search for evidence was carried out in seven databases of global, regional, and local character. Through the application of 115 search strategies the identification of 4,253 documents was achieved: Pubmed (2196), Redalyc (255), Scielo (49), CTSVO* (34), Science Direct (984), Scopus (415) and Embase (320). To define the search strategies, based on all the information on educational innovation reviewed throughout the development of the research, a list of 69 terms (simple and compound) related to educational innovation was created. Prior to the application of the strategies, the accuracy of the terms was verified in the DeCS platform (Descriptors in Health Sciences), and in the MeSH platform (Medical Subject Headings), in Spanish, Portuguese and English. Applying as a first selection criterion the title of each of the 4,253 articles, a screening of 376 evidences was obtained. A first exclusion of 287 documents was made because 195 corresponded to duplicate documents and the abstracts of 92 denoted not to be relevant for the purposes of the present investigation. To these 89 documents, 5 articles obtained from other sources were added: search alerts on specialized pages (3), and sent by colleagues (2). When evaluating these 94 documents, it was found that 80 of them did not meet the inclusion criteria (no full text, language other than English, Spanish or Portuguese, no homologation or indexing of the journal in the year of publication of the article, not scientific articles) to reach a final figure of 14 evidences, which were evaluated with the instrument of the Scottish Intercollegiate Guidelines Network - SIGN, and analyzed using the statistical software SPSS - Statistical Package for the Social Sciences. The countries that published the articles included in the research were Australia (28.57%), United States of America (28.57%), United Kingdom (21.42%), Holland (14.28%), and Switzerland (7.14%). 100% of the articles were written in English. The types of study found were Systematic Review (7.14%), Cohort Study (7.14%), Randomized Clinical Trial (28.57%) and Transversal Epidemiological Study (57.14%). The evidence found shows that in optometry there are few studies that provide sustenance beyond the description. It also shows the need for more research of high-quality methodology to explore innovations in the field of optometry education. In addition, the evidence found is very useful and can be used in our countries at different levels.