Physical activity is a factor of the first magnitude among those that condition human health. In adults, it is a determinant of the risk of cardiovascular mortality, the evidence on its effects on children is lower, but many studies suggest a close relationship with the development of obesity and with cardiovascular risk factors. Objective: To establish the social determinants of health as predictors of healthy physical condition in school children between 12 and 18 years of age in the city of Villahermosa Tolima. Methodology: descriptive-transversal study with comparative phase. The sample design was probabilistic (simple random sampling, MAS). It used a sample of 308 students enrolled in randomly selected public and private institutions with a margin of error of 0.6 cm and a reliability of 95%. For the evaluation of the physical condition the Alpha Fitness battery was used and the determinants were provided by means of a survey with structured questions, a univariate analysis of the categorical variables was made through the frequency distribution, a bivariate analysis through the chi square to determine the degree of association between the variables and a multivariate analysis where the construction of a logit non-linear regression model was performed. Results: 61% of the participants presented an unhealthy physical condition, the social determinants affiliation to the health system, housing condition and the individual Determinants the sex, the age, the way to travel to school, sports, frequency of practice and duration of sport practice, are statistically significant with physical condition. Conclusions: The social determinants that predict physical condition are age (OR 2.039) and sex (OR1.66). The model has a percentage of correct answers of 64.3%, which indicates that it has an acceptable explanatory capacity.