Objective. To establish the relationship between birth weight and neuropsychological maturity in preschool students of one public school and one private school from the city of Tunja, Colombia, and equally the differences between the type of institution and the sex of the participants. Method. Using a cross sectional correlational-descriptive study, a group of 72 children from 36 to 78 months (M = 54.19, SD = 9.88) was evaluated with the questionnaire of Neuropsychological Maturity (CUMANIN). The weight of the children was registered with information from the parents and checked with the birth card. Results. Meaningful differences 1 Este articulo es parte de los productos del proyecto de investigacion aprobado y financiado por la Direccion de Investigaciones de la Universidad Pedagogica y Tecnologica de Colombia. Codigo SGI1589 titulado: “Diseno, implementacion y evaluacion de un programa de correccion neuropsicologica en ninos de 3 a 6 anos de la ciudad de Tunja” 2 Psicologo. Grupo de Investigacion de Psicologia Clinica y de la Salud. Tel. 3124298408. Correo de correspondencia: javierhumberto.parra@uptc.edu.co 3 Doctora en Neurociencias 4 Estudiante de ultimo ano de Psicologia UPTC JAVIER HUMBERTO PARRA PULIDO, LUCIA CARLOTA RODRIGUEZ BARRETO Y JULIAN DAVID CHINOME TORRES 66 were found only between birth weight and the subscale of psychomotricity (p = 0.265, CI = 95%). Girls perform better than the boys. The verbal scale with better performance was presented in the participants of the private school. Conclusion. Birth weight can be related with the psychomotor development, the results confirm the findings obtained previously by comparing the sex and the type of institution to which the children attend.