In recent years there have been food trends or types of diets for clinical purposes in order to improve weight loss that has a high incidence in chronic non-communicable diseases, within these fad diets is intermittent fasting that, despite not being so recent, given that it has been used for hundreds of years, there has been great interest in the benefits attributed to it. This review article aims to clarify a little more the current panorama of intermittent fasting and its metabolic benefits through different mechanisms and what its recommendations for use may be, through the use of databases such as PubMed, Scielo, ScienceDirect and others. In which it was found that the protocol or diet called intermittent fasting does have positive effects on biochemical markers that directly affect the lipid profile, improves insulin sensitivity, improves the body's response to stress and greatly reduces body weight. helping to prevent and improve the quality of life of people who suffer from NCDs, however more research is needed, since it has been shown that many of these benefits are attributed to weight loss as such. Likewise, according to current evidence, it was possible to reach a consensus on which were the most suitable population groups for this type of treatment, resulting in populations with high rates of obesity, CNCD, of course, depending on the adaptation of the patient to it.