Objective: the goal of this study is to describe the sedative and analgesic schemes more often used for the adult patients who are admitted to the intensive care units (ICU) at Organizacion Sanitas Internacional (OSI) in relation to the level of sedation and pain control. Methods: this was an observational, descriptive and multicentre study in 3 ICU at OSI in Bogota, Colombia. Patients who were admitted to the unit with requirement for sedation and analgesia during the period between March 2010 and November 2011 were included in this study. The sedative and analgesic schemes were described, as well as their relationship with variables such as mechanical ventilation time, stay duration in the unit, type of diagnosis and mortality. Results: 1013 patients who were admitted to the surgical UCI and cardiovascular UCI at Clinica Universitaria Colombia and UCI at Clinica Reina Sofia were evaluated. The average age was 62 years old and the average Apache II score was 11. 39.3% of the patients required sedation. Benzodiacepines particularly Midazolam was most often used in 42.5% of the cases. 53.2% of the patients required analgesics drugs. The most often analgesic drug used was Fentanyl in 46.9% of the cases. The sedoanalgesic schemes were performed in 68.7% of the patients, with Fentanyl – Midazolam scheme used in 40.9% followed by Dexmedetomidin in 7.8% of the cases. The RASS average was -3 with an average Verbal Numeric Scale of 3 and an average of Campbell Scale of 4. The least mechanical ventilation time and the last stay time in the unit were observed with Propofol + Dexmedetomidin scheme. Conclusion: 68.7% of the patients admitted to the ICU at OSI required sedation and analgesia. The most often scheme used was Fentanyl – Midazolamin in 40.9% of the cases. The least mechanical ventilation time and least stay time was observed in the group of Propofol – Dexmedetomidin scheme. The RASS average in this study was -3 with average Verbal Numeric Scale of 3 and average Campbell Scale of 4.