Introduction: Acute Respiratory Diseases are a group of diseases affecting the respiratory system and are among the first three causes of death in children under 5 years of age, and hence is considered a public health problem. Objective: To describe the characteristics associated with the occurrence of Acute Respiratory Diseases in children under 5 years of age, cared for at a Healthcare Center in Cali city. Methodology: Descriptive cross-sectional study. Through a census at a Service Provider from August to December 2014, a manual medical record review of diagnoses associated with Acute Respiratory Diseases was completed. Then, a questionnaire was administered in the course of an interview and through observation to caregivers addressing demographics, socioeconomic, clinical and environmental aspects. The statistical processing used Epi-Info version 7.1.5.2. Results: 47 patients were evaluated and the Acute Respiratory Diseases manifested in various clinical forms, with a prevalence of rhinopharyngitis, asthma, and pneumonia, representing 51.1 %, 12.8%, and 10.6% respectively. 40.4 % showed improved clinical conditions after 14 days, followed by 30-day improvement (31.9%) possibly due to environmental and family education related factors at home. Conclusion: There is a need to identify family and community-associated factors relating to the presence and evolution of Acute Respiratory Diseases, in order to establish comprehensive interventions that improve the health status of children and reduce the morbidity and mortality associated with this condition.