Measure out-of-pocket health spending in hypertensive users (278) of the municipality of San Jose de Caldas of the contributory and subsidized regimes of the SGSSS according to their clinical and socioeconomic conditions. Material and methods: Direct and indirect observation techniques were used. The study design was descriptive because it determines the composition of health spending in a group of hypertensive patients from the San Jose de Caldas municipality (278). It also establishes the relationship between out-of-pocket health care spending by hypertensive users, with and without target organ injury, and monthly income through an econometric model that estimates the marginal propensity to consume in health. Results: Highly significant relationship between the presence of target organ injury and health status, as it implies a greater commitment to it and represents a cause of higher out-of-pocket expenses; Dependence was found between target organ injury and severity of hypertension; work disability only occurred in patients with target organ involvement, although in a low percentage; the highest averages of out-of-pocket costs correspond to transportation, medical consultation and dental services. Conclusions: Out-of-pocket costs for the treatment of hypertensive patients increases in patients with target organ damage. Although said expense is not catastrophic, the follow-up and surveillance of these patients is a priority in the SGSS given the impact on quality of life and health care costs.