For to aim the prevalence of Blastocystis spp. and other enteroparasites in patients treated in the Clinical Laboratory of the Dr. Adolfo Pons” Hospital of Maracaibo, Zulia State during 2017-2018, a descriptive, prospective and cross-sectional study was carried out. 4,982 samples of human feces with ages ranging from 0 to 101 years were evaluated. By direct examination with physiological saline solution and lugol staining, a prevalence rate of 28.66% was obtained, highlighting the Blastocystis spp. chromist, and the protozoa belonging to the Entamoeba complex (Entamoeba histolytica / E. dispar / E. moshkovskii / E. bangladeshi) and Giardia duodenalis with 15.03; 8.97 and 4.56% respectively. There were no differences in the distribution by sex, but yes by age groups, children 0-9 years old and those over 70 being the most affected (probability < 0.0001). The most frequent association was established between Blastocystis spp. and the Entamoeba complex with a 26.46% of prevalence in the group of bi and poliparasites. When applying the odds ratio (OR) and prevalence rate (PR), factors associated with intestinal infections could be inferred: stratum IV of Graffar-Mendez-Castellano, solid waste collection and drinking water quality (risk factors); on the contrary, the availability of aqueduct was considered a protective factor. The acute political, social and economic crisis threatens the quality of public health care services in Venezuela and accentuates the problem of infections and intestinal diseases in the western of the country.