This review article attempts to demystify topic of research in clinical nursing. It initially presents a vision about what science and research are which emphasizes the reasons both basic and clinical areas are fundamental to the field of health. Subsequently, the article analyzes the contributions that science and research have made to providing nursing with its identity. Similarly, it provides details about the steps and key elements for conducting research. Then it posits the importance of making clinical research visible and provides research strategies up until the publication of the research. Through all of this, the article shows that science and research are practical human practices which can be conducted as part of patient care and which result in developing scientific rigor in the practice of the profession.