Business literature recognizes that entrepreneurship is one of the elements that positively contributes to economic growth. Similarly, it recognizes that the university context is an important generator of new business initiatives, which can be framed within the University Social Responsibility, a term derived or adapted from the theoretical frame of Corporate Social Responsibility. Entrepreneurship in the university context has a high impact on the generation and strengthening of Social Capital, however, no theoretical or empirical studies have been found in the literature that relate these theoretical elements and analyze comparatively the behavior of variables in publics and private universities in emerging regions like Colombia. This work aims to analyze the relationship between entrepreneurial attitudes and their capacity to generate social capital from university social responsibility frame in students of public and private institutions in Barranquilla, Colombia. Our study contemplates a descriptive quantitative paradigm approach and a non-experimental field design. The survey was used as a technique, using a Likert-type scale questionnaire, applied to a sample of 200 students in two institutions. Results confirm that entrepreneurship is a strong social capital generator in university context and that there are no significant differences between public and private universities in this regard. Conclusions and recommendations are presented aimed at strengthening support networks around university entrepreneurship and the development of new research projects that strengthen the field of study.