The present work was based on the synthesis of gold and silver nanoparticles, which have optical properties and can be used in applications in the biomedical field. For its synthesis, the bottom-up methodology was implemented based on a precursor compound: chloroauric acid for gold nanoparticles and silver nitrate for silver nanoparticles. In this synthesis methodology, some parameters were modified in order to obtain nanoparticle systems with different size and concentration. Three different reducing agents were proposed: sodium borohydride, ethylene glycol and ascorbic acid for silver nanoparticles, and for gold nanoparticles, sodium citrate, citric acid and sodium borohydride. Stabilizers such as polyvinylpyrrolidone (PVP) and potassium citrate were also used. The systems obtained were studied by UV-Visible spectrophotometry, transmission electron microscopy (TEM) and atomic absorption, obtaining similar results to the reported in scientific literature. Silver nanoparticles systems were used as bactericidal agents, specifically tests on bacteria cultures of Escherichia Coli, Staphylococcus epidermidis and oral bacterial. The results indicate that the bactericidal effects are linked to the concentration of silver nanoparticles. On the other hand, and knowing the biocompatibility properties of gold nanoparticles, with the synthesized systems, biocompatibility tests were carried out in platelet rich plasma, observing that the gold nanoparticles have a better performance.