The Colombian government seeks, through fiscal regulations, the massification of electronic invoicing in those responsible for VAT and consumption tax, forcing them to adopt this information system in their organizations; The present research work aims to analyze the influences of the adoption of electronic invoicing at the organizational level, which initially are not detected by managers, administrators and / or collaborators. In the development of the phases of the Multimethodology, with the application of a case study, the contributions for the adoption of electronic invoicing provided in various research studies at the national and international level are initially identified and classified into the strategic, transactional, informational and transformational of an organization; Subsequently, assessment metrics are identified at the organizational level provided by evaluation models of information systems, which are associated with the contributions detected by adoption of electronic invoicing and, finally, a survey-type questionnaire with Likert scale parameters is structured and applied to 72 employees of an entity. The answers provided were tabulated and analyzed, making it possible to determine that the adoption of electronic invoicing does influence the organization at a strategic, informational, transactional and transformational level.