Introduction : Despite the efforts, the tuberculosis control goals have not been achieved due, in large part, to problems of management of the tuberculosis programs. 2015 was a milestone in the fight against tuberculosis in Colombia. Objective : To evaluate the processes and capacities of the Stop Tuberculosis Strategy in Valle del Cauca, Colombia to generate useful knowledge for making strategic and operational decisions for all stakeholders. Methods : The study is framed within what is called evaluative research. The design of the general evaluation was a mixed approach (qualitative-quantitative), and in particular, the processes and capabilities component had a qualitative approach. The analysis period was 2008-2014 and the information was collected in 2015-2016 and analyzed in 2016-2017. Results : Progress was evident in the inclusion of the Strategy in territorial and institutional plans, as well as in the development of monitoring tools, but low levels of inter-program coordination and institutionalization of drug management. Scant adaptation of strategies was observed for prevention, recruitment, detection and monitoring of patients to local realities, as well as a low degree of articulation of strategic alliances between institutions and the community, and few knowledge management processes. Conclusions : There is a chain of weaknesses that explains poor local and departmental performance. Each institution complies with what is established in the norm, doing what they can with what they have, with a low strategic approach to tactic both at the territorial and institutional level.