This work aims to describe the behavior of the indices of the stock exchanges that make up the Latin American Integrated Market in the first five months of 2020 in an approximation to establish the impact of the pandemic generated by the COVID-19 virus that entailed to the implementation of isolation and quarantine measures in several countries that ended up affecting the markets, through a horizontal analysis the monthly percentage variation of infections was established for each country in the same way the relative change of the different stock market indices, it was appreciated how it impacted significantly the global spread in the behavior of the stock markets studied, evidencing the sharp drop specifically in the aftermath of the announcement by the World Health Organization that implied the confinement and therefore the paralysis of different economic activities, it is important stand out as a conjunctural factor reverberates in the regional and global economy.