Introduction: Heart failure is one of the most frequent causes of hospitalization in intensive care services, with a high rate of morbidity and mortality. For this reason, it becomes a priority to identify, prior to discharge, the precipitating factors for readmission, with adherence to treatment and social support being the most important. Objective: To determine the relationship between the level of adherence to pharmacological and non-pharmacological treatment and the social support of patients with heart failure. Methodology: A correlational study was carried out with a sample size of 64 patients with a diagnosis of CF. A non-probability sampling was used. To measure the level of adherence, the scale for evaluation of adherence behaviors with a Cronbach's alpha of 0.72 was used, and for social support the Medical Outcomes Study Social Support (MOS) scale with a Cronbach's alpha of 0 was used. 94. A descriptive analysis was carried out and Fisher's test of independence of categorical distributions was applied to establish the relationship between the level of adherence and social support. Results: Most of the participants had a level of frequently adherent to treatment (78%). The global index of social support was medium level (mean: 76.18-SD + -16.5). A moderate association was found between the level of emotional support (p: 0.006336) and the level of affective support (p: 0.03025) with adherence to treatment. Conclusions: It is essential that the nursing professional includes the evaluation of social support prior to discharge, in order to optimize the levels of adherence. Keywords: Social support, compliance and adherence to treatment, heart failure (DeCS)