The obesity is considered the 21st century pandemic and its prevalence in the world is increasing, this pattern is observed in Colombia according to the results of the ENSIN 2010 and 2015. This disease is caused by an energy imbalance lead by a low energy expenditure in sedentary individuals and overconsumption of high energy foods, which can be considered as an addictive like behavior in specific conditions determined in the Yale food addiction scale. The neurobiological and behavioral changes exhibited in obese people with food addiction can be associated to the activity of the endocannabinoid system in the central nervous system, given the fact that obese population have high rates of consumption of food rich in linoleic acid or 6 omega, which derivative form, the arachidonic acid is the main precursor of endocannabinoids, compounds that have increased plasmatic levels in obese people. The main purpose of this study is to determine the association between plasmatic levels of arachidonic acid and diagnostic criteria of food addiction in obese adults after inducing changes in the essential fatty acids intake. This thesis consists in a prospective quasi-experimental with clinical trial model, non-randomized, single-blind, crossover pilot study, conducted in obese adults whom were offered two nutritional treatments of obesity, one of these with a decrease in the omega 6 consumption and an increase in the omega 3 intake. The main findings indicate a positive correlation between arachidonic acid plasmatic levels and the scoring in the food addiction scale in individuals exposed to the experimental nutritional treatment. These results are held by the statistically significant decrease in plasmatic levels of arachidonic acid, the score in the food addiction scale, the body weight and the triglycerides plasma concentration found in the participants who had received the intervention that modified the consumption of essential fatty acids. Other variables such as body fat percentage and plasmatic levels of total cholesterol, HDL and LDL did not exhibit expected behaviors according to the literature, so it is thought that the time of exposure to interventions was not enough in order to get significant changes in such