The Constitutional Court, in Judgment T622 of 2016, recognized the Atrato River as a subject of rights and its legal representation was granted by the Ministry of Environment and Sustainable Development. This reflection article aims to show, in the context of the 2016 Judgment T622, some central elements for its implementation, which seeks to highlight the need for new conceptual, practical, and public policy developments so that the actions undertaken ensure their protection, conservation, maintenance, and restoration, which must be effective and realistic. In this way, the protection of the fundamental rights of the inhabitants can be achieved and the socio-environmental degradation and conflicts can be minimized.