The objective of the present investigation was, to set forth the attitudes of the health professionals and the hospital clowns of the city of Cali, regarding the Laughter Therapy, taking it into account as an Alternative and Complementary Therapy. A qualitative study was carried out, by means of thirteen semi-structured interviews, taking as sample nine health professionals (doctors, nurses and psychologists) and four hospital clowns. It was found that Laughter Therapy is known in the field of health, as a job that hospital clowns commonly do, with the objective of ensuring the whole wellbeing of a people of different ages and in various clinical states, through laughter and humor; helping to reduce the psychological, physical, social and emotional symptoms of each person and reduce the dehumanization factor of health care. Therefore, as a conclusion, it is vital to emphasize the importance of integrating the Laughter Therapy into the health professional’s attention and considering it a supporting complement to Conventional Medicine; however, there is little interest in this topic and in general in the CAT, by the health system, the health professionals and the Colombian society. This is due to the lack of knowledge and value given to the emotional aspect of a hospitalized patient and insufficient evidence of long-term changes in patient’s health.