The objective of this text is to review the incidence of resilience and overload in caregivers of children with oncological diseases, resilience being defined as the ability to overcome adverse situations, as opposed to overloading, which refers to chronic stress associated with care, which can affect the physical and psychological health of the caregiver, considerably modifying the performance of their role. This research was validated by means of a cross-sectional study in which 50 articles were analyzed, including academic articles and articles from scientific journals, in order to validate concepts, findings and advances in correspondence to the relationship between overload and resilience, identifying possible variables that affect this relationship. From this, it became evident that spirituality and adequate coping strategies can modify the levels of resilience and overload, in addition to this, various tools are proposed for the prevention of overload and the promotion of coping strategies in the work of care