Early neonatal sepsis is defined as a syndrome of systemic inflammatory response, in the presence or with suspected infection in the newborn. It is a diagnostic challenge for the health team since their symptoms are nonspecific, and in some cases being absent, with only the suspicion of this due to the presence of risk factors, which makes it essential to perform timely management. This pathology is a problem for public health, since it generates high rates of morbidity and mortality at the national level. In Bogota, its incidence is 1.8 cases per 1000 live births, but even so the distribution of the most prevalent risk factors in the study sites is not clear, for which reason their study would improve the contingency plans regarding said pathology. Therefore, a descriptive cross-sectional study was carried out to identify the frequency distribution of the risk factors, among which it is found that the main one is chorioamnionitis with a percentage of presentation of 30.84%, followed by the prolonged rupture of membranes 23.36%. In addition to this it was evidenced that in some cases the diagnosis was made in patients with less than 4 prenatal controls, being this way in 16.8% of the cases. For diagnosis and monitoring, laboratories are of the utmost importance, such as blood cultures, where it is striking that in neither case are both positive.